Publication

A machine learning approach using conditional normalizing flow to address extreme class imbalance problems in personal health records

Yeongmin Kim, Wongyung Choi, Woojeong Choi, Grace Ko, Seonggyun Han, Hwan-Cheol Kim, Dokyoon Kim, Dong-Gi Lee, Dong Wook Shin, Younghee Lee

2024

BioData Min .

TREM2 splice isoforms generate soluble TREM2 species that disrupt long-term potentiation

Miguel Moutinho, Israel Coronel, Andy P. Tsai, Gonzalo Viana Di Prisco, Taylor Pennington, Brady K. Atwood, Shweta S. Puntambekar, Daniel C. Smith, Pablo Martinez, Seonggyun Han, Younghee Lee, Cristian A. Lasagna-Reeves, Bruce T. Lamb, Stephanie J. Bissel, Kwangsik Nho, Gary E. Landreth

2023

Genome Med .

Brain regional alternative splicing and clinical traits in Alzheimer’s disease

Sara Kim, Seonggyun Han, Kwangsik Nho, Younghee Lee, Insong Koh

2023

BASIC SCIENCE AND PATHOGENESIS

Brain Region-Dependent Alternative Splicing of Alzheimer Disease (AD)-Risk Genes Is Associated With Neuropathological Features in AD

Sara Kim, Seonggyun Han, Soo-Ah Cho, Kwangsik Nho, Insong Koh, Younghee Lee

2022

Int Neurourol J .

Interplay of genetic and epigenetic factors in regulating immune-related pathways in Alzheimer’s disease

Seonggyun Han, Kwangsik Nho, Younghee Lee

2022

BASIC SCIENCE AND PATHOGENESIS

ADAS-viewer: web-based application for integrative analysis of multi-omics data in Alzheimer’s disease

Seonggyun Han, Jaehang Shin, Hyeim Jung, Jane Ryu, Habtamu Minassie, Kwangsik Nho, Insong Koh, Younghee Lee

2021

NPJ Syst Biol Appl.