Our research contributes to this endeavor by focusing on the study of characterizing the systems-level properties and genetic/molecular basis of human disease by integrating and interpreting genomics and transcriptions data.

For decades, high throughput technologies have succesfully captured diverse genome-wide sequence information, quantative gene expression, and regulatory information. The generation of huge volumes of data by these technologies, 'omics'have made remarkable contributions to building a comprehensive list of functional elements in the human genome. We are still learning how to translate these data into biological and clinical knowledge. The primary challenge at hand is determining how to connect genotype with phenotype using those data.